The associations could be due to metabolic irregularities in amino acid biosynthesis and drug metabolism, which may help explain how PFAS affect the body’s ability to regulate blood sugar.
Exposure to a class of synthetic chemicals known as per- and polyfluoroalkyl substances (PFAS)—often called “forever chemicals”—may increase the risk of developing type 2 diabetes, according to a new study led by Mount Sinai researchers. The findings were published today in eBioMedicine.
The team conducted a nested case-control study (an observational study that is conducted within a larger cohort study) within BioMe, a large, electronic health record-linked research database comprising records of more than 70,000 study participants who have sought care at The Mount Sinai Hospital in New York City since 2007.
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