Wednesday, June 17, 2026
Location
This program is in person only.
University of Bordeaux Legal & Judicial Centre (PJJ)
35 Pl. Pey Berland, 33000 Bordeaux, France
Google Maps
Day #1: Wednesday, June 17, 2026
9:00 – 12:00
Check In, Pick up Credentials
9:30 – 11:00
Pre-Symposium Workshops (concurrent – select 1, pre-registration required)
Workshop A: Untargeted Exposomics for AD/ADRD Research
Dinesh Barupal, PhD, Associate Professor, Environmental Medicine, Icahn School of Medicine at Mount Sinai, USA
Click here to read workshop description
This workshop will introduce researchers to the transformative potential of untargeted exposomics in understanding environmental contributions to Alzheimer’s Disease and Related Dementias (ADRD). Untargeted exposomics goes beyond traditional methods that target specific exposures, such as lead or BPA, by utilizing advanced analytical techniques, such as high-resolution mass spectrometry to detect a broad spectrum of environmental chemicals, biological agents, and endogenous metabolic changes. Dr. Dinesh Barupal will share examples highlighting the success of untargeted exposomics in biobank studies, showcasing the ability to reveal previously unrecognized exposure-disease relationships.
OR
Workshop B: Geographic Information Systems (GIS) and Environmental Exposures
Itai Kloog, PhD, Professor, Environmental Medicine, Icahn School of Medicine at Mount Sinai, USA
Mike He, PhD, Instructor, Environmental Medicine, Icahn School of Medicine at Mount Sinai, USA
Click here to read workshop description
This workshop will introduce GIS concepts and their application in exposomic research studies, with a focus on temperature and air pollution. Dr. Itai Kloog will focus on introducing key concepts in GIS, including projections, working with spatial data, base mapping concept, geocoding, visualization, and thematic mapping. He will also give some examples from recent studies applying these tools in environmental epidemiology. Dr. Mike He will demonstrate examples of real-life GIS use in exposure assessment studies and help participants go over some hands-on exercises. Participants will gain insights through case studies on how to leverage GIS tools for spatial analysis in exposure assessment studies, emphasizing the visualization and interpretation of environmental data.
11:00 – 12:00
Lunch Available
12:00 – 12:30
Welcome and Opening Remarks
Cécilia Samieri, DVM, PhD, Director of Research, French National Institute of Health and Medical Research (INSERM), Bordeaux Population Health Research Center, France
Rodolphe Thiébaut, MD, PhD, Director, Bordeaux Population Health Research Center, the French National Institute of Health and Medical Research (INSERM), France
Robert Wright, MD, MPH, Ethel H. Wise Professor and Chair, Department of Environmental Medicine, and Co-Director, Institute for Exposomic Research, Icahn School of Medicine at Mount Sinai, USA
12:30 – 13:00
Day #1 Keynote: The Core Aims of Exposomic Research
Rémy Slama, PhD, Senior Investigator, INSERM and Professor, École Normale Supérieure, Paris, France
13:00 – 13:30
Natural Disasters and Dementia: A Bad Combination for Aging Populations
R. Sean Morrison, MD, FAAHPM, Ellen and Howard C. Katz Professor and Chair, Brookdale Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai, USA
13:30-14:00
Applying the Exposome Framework to Advance Alzheimer’s Disease and Related Dementias Research: Opportunities for Precision Prevention and Early Risk Detection
Richard Kwok, PhD, Program Director, Population Studies and Genetics Branch, Division of Neuroscience, National Institute on Aging, USA
14:00 – 14:45
Poster Session #1 and Coffee Break
14:45 – 15:15
Integrating Life-course Perspectives to Understand the Impacts of Exposome on Healthy Aging
Jinkook Lee, PhD, Professor of Economics and Director of the Program on Global Aging, Health, and Policy, University of Southern California, USA
15:15 – 15:45
Assessing the Contribution of the Chemical Exposome to Brain Aging
Cécilia Samieri, DVM, PhD, Director of Research at the French National Institute of Health and Medical Research (INSERM), Bordeaux Population Health Research Center, France
15:45 – 16:00
Open Cheminformatics Data Exchange Supporting Untargeted Exposomics
Emma Schymanski, Dr. rer. nat., Full Professor in Environmental Cheminformatics, Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Luxembourg
16:00 – 16:15
The Comparative Toxicogenomics Database: A resource for exploring exposure effects on neurological diseases
Carolyn Mattingly, PhD, Distinguished Professor, Department of Biological Sciences, NC State University, USA
16:15 – 16:30
Exposome Correlation and Interpretation Database (ECID)
Dinesh Barupal, PhD, Associate Professor, Environmental Medicine, Icahn School of Medicine at Mount Sinai, USA
16:30 – 17:15
Panel Discussion: Exposomic Data Science Applications Relevant to ADRD
Emma Schymanski, Dr. rer. nat.
Carolyn Mattingly, PhD
Dinesh Barupal, PhD
Moderator: Gary Miller, PhD, Vice Dean for Research Strategy and Innovation, Professor of Environmental Health Sciences in the Mailman School of Public Health at Columbia University in New York, USA
17:15
Presentations end
All attendees walk to Ponton d’Honneur to take boat (~25-minute walk)
18:00
Boat departs from Ponton d’Honneur (See Google Map for departure location)
19:00
Networking Dinner (Optional, off-site)
22:00
Bus returns to city center (~30-minute drive)
Day #2: Thursday, June 18, 2026
8:00
Coffee available
9:00 – 9:10
Welcome
R. Sean Morrison, MD, FAAHPM, Ellen and Howard C. Katz Professor and Chair, Brookdale Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai, USA
9:10 – 9:40
Day #2 Keynote: The Exposome at 21: How Did We Get Here and Where Are We Going?
David Balshaw, PhD, Director, Division of Extramural Research and Training, National Institute of Environmental Health Sciences, USA
9:40 – 10:10
Developmental Origins of Alzheimer’s Disease
Robert O. Wright, MD, MPH, Ethel H. Wise Professor and Chair, Department of Environmental Medicine, and Co-Director, Institute for Exposomic Research, Icahn School of Medicine at Mount Sinai, USA
10:10–10:40
In Silico Exposomics of Alzheimer’s Disease and Related Dementias
Brad Racette, MD, Kemper and Ethel Marley Chair for Neurology, and Senior Vice President at Barrow Neurological Institute, USA
10:40 – 11:10
Nutrition and Cognition
Nikolaos Scarmeas, MD, MS, PhD, Professor of Neurology, Medical School, National and Kapodistrian University of Athens, Greece and Columbia University, USA
11:10 – 13:00
Poster Session #2 and Lunch
13:00 – 13:30
Challenges and Opportunities in Exposome Studies of Parkinson’s Disease
Alexis Elbaz MD, PhD, Director of Research, French National Institute of Health and Medical Research (INSERM), Centre for Epidemiology and Population Health, France
13:30 – 14:00
Multidomain Approaches to Prevent Cognitive Decline
Sandrine Andrieu, MD, MPH, Professor and Chair, Department of Clinical Epidemiology and Public Health, Toulouse University Hospital, IHU HealthAge, CERPOP, France
14:00 – 14:30
Fields of Risk: Mapping the Exposome Landscape of Parkinson’s Disease
Roel Vermeulen, PhD, Professor of Environmental Epidemiology and Exposome Science, Utrecht University and University Medical Center Utrecht (UMCU), The Netherlands
14:30 – 15:00
From Hormonal Signatures to Brain Health across Generations: Exposome Predictors of the Pregnancy Steroid Milieu, Child Neurodevelopment, and Maternal Postpartum Depression Risk
Léa Maitre, PhD, Assistant Research Professor and ISG Exposome Hub Coordinator, ISGlobal, Barcelona Institute for Global Health, Spain
15:00 – 15:45
Group Photo and Break
15:45 – 16:00
Sleep as a Window into the Aging Brain
Yue Leng, PhD, Associate Professor, Department of Psychiatry and Behavioral Sciences, Bakar Computational Health Sciences Institute, University of California, San Francisco, USA
16:00 – 16:15
Plasma Molecular Signatures of ADRD for Early Diagnosis
Fanny Elahi, MD, PhD, Associate Professor in the Departments of Neurology, Neuroscience, Pathology, Molecular and Cell-based Medicine, and Artificial Intelligence and Human Health, Icahn School of Medicine at Mount Sinai, USA
16:15 – 16:30
Interplay between Exposomics and ADRD Phenotypes
Carole Dufouil, PhD, Director of Research, French National Institute of Health and Medical Research (INSERM), France
16:30 – 17:15
Panel Discussion: Prodromal Biomarkers and Diagnostic Advances in ADRD: opportunities to integrate Exposomics
Yue Leng, PhD
Fanny Elahi, MD, PhD
Carole Dufouil, PhD
Moderator: Robert Barouki, MD, PhD, Professor of Biochemistry, Université Paris Cité and Head of the Public Health Institute at the French National Institute of Health and Medical Research (INSERM), France
17:15
Day #2 ends; Free evening for attendees
Day #3: Friday, June 19, 2026
8:00
Coffee available
9:00 – 9:10
Welcome
Robert O. Wright, MD, MPH, Ethel H. Wise Professor and Chair, Department of Environmental Medicine, and Co-Director, Institute for Exposomic Research, Icahn School of Medicine at Mount Sinai, USA
9:10 – 9:40
Using Exposomics to Define the Trajectory of Alzheimer’s Disease
Gary Miller, PhD, Vice Dean for Research Strategy and Innovation, Professor of Environmental Health Sciences in the Mailman School of Public Health at Columbia University in New York, USA
9:40 – 10:10
Mapping the Human Chemical Exposome of Neurodegenerative Diseases
Arthur David, PhD, Professor, French School of Public Health, Research Institute for Environmental and Occupational Health (Irset), Rennes, France
10:10 – 10:40
Break
10:40 – 11:10
Novel Exposome Biomarkers for Neurological Disorders
Manish Arora, BDS, MPH, PhD, Edith J. Baerwald Professor and Vice Chairman of the Department of Environmental Medicine, Icahn School of Medicine at Mount Sinai, and Co-Founder and CEO, LinusBio, USA
11:10–11:40
Mapping the Microbiome-Gut-Brain Axis Across Neuropsychiatric and Neurodegenerative Conditions
Mireia Valles-Colomer, PhD, Professor and Group Leader in Microbiome Research at the Medicine and Life Sciences Department, University Pompeu Fabra, Barcelona, Spain
11:40 – 12:10
Exposome Analytics: Overview and Perspectives
Marc Chadeau-Hyam, PhD, Professor of Computational Epidemiology and Biostatistics, School of Public Health, Faculty of Medicine, Imperial College London, United Kingdom
12:10 – 12:20
Poster Awards
12:20 – 13:00
Lunch
13:00 – 15:30
Next Steps Collaboration Session “Advancing a Global Human Exposome Project”
This afternoon session will feature moderated panel discussions on advancing a global human exposome initiative. Attendees will hear updates from regional exposome networks worldwide, including the Exposome Forum, NEXUS, GECC, and IHEN. Panels will focus on strengthening global research collaborations and capacity building, as well as on integrating exposomics into aging research.
13:00 – 13:10
Welcome and Introductions
Robert Wright, MD, MPH, Ethel H. Wise Professor and Chair, Department of Environmental Medicine, and Co-Director, Institute for Exposomic Research, Icahn School of Medicine at Mount Sinai, USA
Rick Woychik, PhD, Senior Advisor to the NIH Director, National Institutes of Health, USA
13:10 – 13:25
Opportunities for EU-US Collaborations
Thomas Hartung, MD, PhD, Doerenkamp-Zbinden Professor and Chair for Evidence-based Toxicology, Johns Hopkins University, Bloomberg School of Public Health, Whiting School of Engineering and School of Medicine, USA (Exposome Forum)
13:25 – 13:50
Updates from Regional Networks
Gary Miller, PhD (NEXUS), Jinkook Lee, PhD (GECC), Roel Vermeulen, PhD (IHEN)
13:50 – 14:30
Panel Discussion on Global Collaborations
Martha M. (Mara) Téllez Rojo, MSc, DSc, Professor, National Institute of Public Health (INSP), Mexico
Shoji Nakayama, MD, PhD, Deputy Director, Japan Environment and Children’s Study Programme Office, National Institute for Environmental Studies, Japan
Robert Barouki, MD, PhD, Professor of Biochemistry, Université Paris Cité and Head of the Public Health Institute at the French National Institute of Health and Medical Research (INSERM), France
Roel Vermeulen, PhD, Professor of Environmental Epidemiology and Exposome Science, Utrecht University and University Medical Center Utrecht (UMCU), The Netherlands
Gary Miller, PhD, Vice Dean for Research Strategy and Innovation, Professor of Environmental Health Sciences in the Mailman School of Public Health at Columbia University in New York, USA
Jinkook Lee, PhD, Professor of Economics and Director of the Program on Global Aging, Health, and Policy, University of Southern California, USA
Moderator: Rick Woychik, PhD, Senior Advisor to the NIH Director, National Institutes of Health, USA
14:30 – 15:20
Panel Discussion on Incorporating Exposomics into Aging Research
R. Sean Morrison, MD, FAAHPM, Ellen and Howard C. Katz Professor and Chair, Brookdale Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai, USA
Brad Racette, MD, Kemper and Ethel Marley Chair for Neurology, and Senior Vice President, Barrow Neurological Institute, USA
Alexis Elbaz MD, PhD, Director of Research at the French National Institute of Health and Medical Research (INSERM), Centre for Epidemiology and Population Health, France
Sandrine Andrieu, MD, MPH, Professor and Chair, Department of Clinical Epidemiology and Public Health, Toulouse University Hospital, IHU HealthAge, CERPOP, France
Nikolaos Scarmeas, MD, MS, PhD, Professor of Neurology, Medical School, National and Kapodistrian University of Athens, Greece and Columbia University, USA
Moderator: Cécilia Samieri, DVM, PhD, Director of Research at the French National Institute of Health and Medical Research (INSERM), Bordeaux Population Health Research Center, France
15:20 – 15:30
Next Steps, Rick Woychik, PhD, Senior Advisor to the NIH Director, National Institutes of Health, USA