Wednesday, June 17, 2026
Day #1: Wednesday, June 17, 2026
10:00 – 11:30
Pre-Symposium Concurrent Morning Workshops
Workshop A: Untargeted Exposomics for AD/ADRD Research
Dinesh Barupal, PhD, Associate Professor, Environmental Medicine, Icahn School of Medicine at Mount Sinai, USA
Workshop B: Geographic Information Systems (GIS) and Environmental Exposures
Itai Kloog, PhD, Professor, Environmental Medicine, Icahn School of Medicine at Mount Sinai, USA
11:00
Check in and Lunch Available
12:00 – 12:30
Welcome and Opening Remarks
Cécilia Samieri, DVM, PhD, Director of Research at the French National Institute of Health and Medical Research (INSERM), Bordeaux Population Health Research Center, France
Rodolphe Thiébaut, MD, PhD, Director, Bordeaux Population Health Research Center, the French National Institute of Health and Medical Research (INSERM), France
Robert Wright, MD, MPH, Ethel H. Wise Professor and Chair, Department of Environmental Medicine, and Co-Director, Institute for Exposomic Research, Icahn School of Medicine at Mount Sinai, USA
12:30 – 13:00
Rémy Slama, PhD, Senior Investigator, French National Institute of Health and Medical Research (INSERM) and Professor at Ecole Normale Supérieure Paris, France
13:00 – 13:30
Natural Disasters and Dementia: A Bad Combination for Aging Populations
R. Sean Morrison, MD, FAAHPM, Ellen and Howard C. Katz Professor and Chair, Brookdale Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai, USA
13:30-14:00
Richard Kwok, PhD, Program Director, Population Studies and Genetics Branch, Division of Neuroscience, National Institute on Aging, USA
14:00 – 14:30
Poster Session #1 and Coffee Break
14:30 – 15:00
Integrating Life-course Perspectives to Understand the Impacts of Exposome on Healthy Aging
Jinkook Lee, PhD, Professor of Economics and Director of the Program on Global Aging, Health, and Policy, University of Southern California, USA
15:30 – 16:00
Assessing the Contribution of the Chemical Exposome to Brain Aging
Cécilia Samieri, DVM, PhD, Director of Research at the French National Institute of Health and Medical Research (INSERM), Bordeaux Population Health Research Center, France
16:00 – 16:15
Open Cheminformatics Data Exchange Supporting Untargeted Exposomics
Emma Schymanski, Dr. rer. nat., Full Professor in Environmental Cheminformatics, Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Luxembourg
16:15 – 16:30
Carolyn Mattingly, PhD, Distinguished Professor, Department of Biological Sciences, NC State University, USA
16:30 – 16:45
Dinesh Barupal, PhD, Associate Professor, Environmental Medicine, Icahn School of Medicine at Mount Sinai, USA
16:45 – 17:30
Panel Discussion: Exposomic Data Science Applications Relevant to ADRD
Emma Schymanski, Dr. rer. nat.
Carolyn Mattingly, PhD
Dinesh Barupal, PhD
17:30
Group walks to Ponton d’Honneur to take boat to networking dinner.
18:00
Boat departs from Ponton d’Honneur (See Google Map for departure location)
19:00
Networking Dinner (Optional, off-site)
22:00
Bus returns to City Center (~30 minute drive)
Day #2: Thursday, June 18, 2026
9:00 – 9:00
Welcome
R. Sean Morrison, MD, FAAHPM, Ellen and Howard C. Katz Professor and Chair, Brookdale Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai, USA
9:10 – 9:40
Day #2 Keynote: The Exposome at 21: How Did We Get Here and Where Are We Going?
David Balshaw, PhD, Director, Division of Extramural Research and Training, National Institute of Environmental Health Sciences, USA
9:40 – 10:10
Robert O. Wright, MD, MPH, Ethel H. Wise Professor and Chair, Department of Environmental Medicine, and Co-Director, Institute for Exposomic Research, Icahn School of Medicine at Mount Sinai, USA
10:10–10:40
In Silico Exposomics of Alzheimer’s Disease and Related Dementias
Brad Racette, MD, Kemper and Ethel Marley Chair for Neurology, and Senior Vice President at Barrow Neurological Institute, USA
10:40 – 11:10
Nutrition and Cognition
Nikolaos Scarmeas, MD, MS, PhD, Professor of Neurology, Medical School, National and Kapodistrian University of Athens, Greece and Columbia University, USA
11:10 – 13:00
Poster Session #2 and Lunch
13:00 – 13:30
Challenges and Opportunities in Exposome Studies of Parkinson’s Disease
Alexis Elbaz MD, PhD, Director of Research at the French National Institute of Health and Medical Research (INSERM), Centre for Epidemiology and Population Health, France
13:30 – 14:00
Multidomain Approaches to Prevent Cognitive Decline
Sandrine Andrieu, MD, MPH, Professor and Chair, Department of Clinical Epidemiology and Public Health, Toulouse University Hospital, IHU HealthAge, CERPOP, France
14:00 – 14:30
Fields of Risk: Mapping the Exposome Landscape of Parkinson’s Disease
Roel Vermeulen, PhD, Professor of Environmental Epidemiology and Exposome Science, Utrecht University and University Medical Center Utrecht (UMCU), The Netherlands
14:30 – 15:30
Group Photo and Break
15:30 – 15:45
Sleep as a Window into the Aging Brain
Yue Leng, PhD, Associate Professor, Department of Psychiatry and Behavioral Sciences, Bakar Computational Health Sciences Institute, University of California, San Francisco, USA
15:45 – 16:00
Plasma Molecular Signatures of ADRD for Early Diagnosis
Fanny Elahi, MD, PhD, Associate Professor in the Departments of Neurology, Neuroscience, Pathology, Molecular and Cell-based Medicine, and Artificial Intelligence and Human Health, Icahn School of Medicine at Mount Sinai, USA
16:00 – 16:15
Interplay between Exposomics and ADRD Phenotypes
Carole Dufouil, PhD, Director of Research, National Institute of Health and Medical Research (INSERM), France
16:15 – 17:00
Panel Discussion: Prodromal Biomarkers and Diagnostic Advances in ADRD: opportunities to integrate Exposomics
Yue Leng, PhD
Fanny Elahi, MD, PhD
Carole Dufouil, PhD
Moderator: Robert Barouki, MD, PhD, Professor of Biochemistry, Université Paris Cité and Head of the Public Health Institute at the French National Institute of Health and Medical Research (INSERM), France
17:00
Day #2 ends; Free evening for attendees
Day #3: Friday, June 19, 2026
9:00 – 9:10
Welcome
Robert O. Wright, MD, MPH, Ethel H. Wise Professor and Chair, Department of Environmental Medicine, and Co-Director, Institute for Exposomic Research, Icahn School of Medicine at Mount Sinai, USA
9:10 – 9:40
Using Exposomics to Define the Trajectory of Alzheimer’s Disease
Gary Miller, PhD, Vice Dean for Research Strategy and Innovation, Professor of Environmental Health Sciences in the Mailman School of Public Health at Columbia University in New York, USA
9:40 – 10:10
Arthur David, Professor at the French School of Public Health, Rennes, France
10:10 – 10:40
Manish Arora, BDS, MPH, PhD, Edith J. Baerwald Professor and Vice Chairman of the Department of Environmental Medicine, Icahn School of Medicine at Mount Sinai, and Co-Founder and CEO, LinusBio, USA
10:40 – 11:10
Break
11:10–11:40
Mapping the Microbiome-Gut-Brain Axis Across Neuropsychiatric and Neurodegenerative Conditions
Mireia Valles-Colomer, PhD, Professor and Group Leader in Microbiome Research at the Medicine and Life Sciences Department, University Pompeu Fabra, Barcelona, Spain
11:40 – 12:10
Marc Chadeau-Hyam, PhD, Professor of Computational Epidemiology and Biostatistics, School of Public Health, Faculty of Medicine, Imperial College London, United Kingdom
12:10 – 12:20
Poster Awards
12:20 – 13:00
Lunch
13:00 – 15:30
Next Steps Collaboration Meeting
This session will feature moderated panel discussions on advancing a global human exposome initiative. Attendees will hear updates from regional exposome networks worldwide, including the Exposome Forum, NEXUS, GECC, and IHEN. Panels will focus on strengthening global research collaborations and capacity building, as well as on integrating exposomics into aging research.
Welcome and Introductions
Robert Wright, MD, MPH, Mount Sinai
Rick Woychik, PhD, National Institutes of Health
Opportunities for EU-US Collaborations
Thomas Hartung, MD, PhD, Exposome Forum
Updates from Regional Networks
Gary Miller, PhD (NEXUS), Jinkook Lee, PhD (GECC), Roel Vermeulen, PhD (IHEN)
Panel Discussion on Global Collaborations
Robert Barouki, MD, PhD, Gary Miller, PhD, Jinkook Lee, PhD, Roel Vermeulen, PhD, Mara Téllez-Rojo, MSc, DSc, Shoji Nakayama, MD, PhD
Moderator: Rick Woychik, PhD
Panel Discussion on Incorporating Exposomics into Aging Research
Sean Morrisson, MD, Brad Racette, MD, Alexis Elbaz, MD, PhD, Sandrine Andrieu, MD, MPH, Nick Scarmeas, MD, MS, PhD
Moderator: Cécilia Samieri, DMV, PhD
Next Steps, Rick Woychik, PhD

